Welcome to circRNADb

circRNADb 1.0, circular RNA (or circRNA) Database version 1.0, is a comprehensive database of circular RNA molecules in humans. It is freely available for non-commercial use. The latest version of this circRNA database contains 32,914 annotated exonic circRNAs, and can be a valuable resource for large-scale studies of circRNA, especially in humans.

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About circRNAs

Circular RNAs are a novel group of abundant, stable, and evolutionary conservative noncoding RNAs. Unlike linear RNA, circular RNA lacks 5' cap and 3' poly(A) tail, it is an RNA molecule with 3' and 5' ends covalently linked in a circle.

Recent studies using high-throughput RNA-seq data and improved computational approach have discoverd thousands of circRNAs across species. Besides, a subset of them can play important roles in gene regulation by acting as microRNA sponges.

Further research on the mechanism of formation and function about circRNA will help us understand the complexity of life activity.